Milestone achievement: the breeding efficiency of hybrid potato in China will be improved by more than 50%

  Many people don’t know that the French fries eaten in KFC and McDonald’s all come from potato varieties bred 120 years ago. As the staple food of 1.3 billion people in the world, potato breeding process is slow, and new breeding methods are urgently needed to reform potato breeding. Therefore, the scientists of China Academy of Agricultural Sciences put forward the "Excellent Potato Plan", the purpose of which is to make people in China and even the whole world eat potatoes with higher yield and better quality.

  At 23: 00 Beijing time on May 4th, 2023, the international authoritative journal Cell published the latest research result of Huang Sanwen’s team of Shenzhen Institute of Agricultural Genomics, Chinese Academy of Agricultural Sciences: "Phylogenetic Discovery of Deleterious Mutations Facilities Hybrid Potato Breeding".

  This research has invented a new "evolutionary lens" technology, which gives breeders a pair of "golden eyes", can find the genome "reef" (which scientists call "harmful mutation") that hinders potato breeding as early as possible, avoid breeding "going the wrong way", and let everyone eat better quality and high yield potatoes faster.

  "We drew the first two-dimensional map of harmful mutations in potato genome, and developed a new model of whole genome prediction by using the map information, which can predict the yield in seedling stage, with an accuracy of 25%-45% higher than before. In this way, materials with low yield can be eliminated at an early stage, thus quickly cultivating high-yield varieties, and the breeding efficiency of hybrid potatoes will be improved by more than 50%. " Huang Sanwen said in an interview with The Paper (www.thepaper.cn).

  "excellent potato plan"

  Potato is the most important tuber food crop, the main food source of 1.3 billion people and the fourth staple food crop in China. Potato has the advantages of high yield, less water consumption and wide planting area. However, because the traditional cultivated potato is autotetraploid and its genome is complex, the breeding process is very slow. In addition, the asexual propagation of potato chips also faces some problems, such as low propagation coefficient, high storage and transportation cost, and easy to carry pests and diseases.

  How to transform tetraploid potato propagated by tuber into diploid hybrid potato propagated by seed is a worldwide problem in potato industry, and it is also the "crown jewel" of seed industry innovation.

  In order to solve the above problems, Huang Sanwen’s team launched the "Excellent Potato Plan" in conjunction with domestic and foreign superior units, aiming at replacing tetraploid with diploid potato, replacing potato block with seed propagation, guiding potato breeding with genomics and synthetic biology, and completely changing the breeding and reproduction methods of potatoes.

  Yang Zhenhai, Party Secretary of China Academy of Agricultural Sciences, said that in recent years, the "Excellent Potato Program" team has successively solved major problems such as potato genome analysis, self-incompatibility and self-decline, and cultivated the first generation of inbred lines and hybrids. The related achievements have been published in top international academic journals, and now the latest achievement of "Identification of harmful mutations by evolutionary genomics" has been published in Cell magazine, which can provide a new scientific basis for potato breeding parent selection and variety improvement. These original basic scientific research achievements have been highly recognized by colleagues at home and abroad, and laid a solid foundation for accelerating the breeding of diploid hybrid potatoes.

  Potato breeding enters the fast lane

  In this study, Huang Sanwen’s team collected a large number of Solanaceae species resources in conjunction with outstanding units at home and abroad, and traced the evolutionary traces of the longest 80 million years and accumulated 1.2 billion years through comparative analysis of 100 Solanaceae genomes. On this basis, an "evolutionary lens" was developed to discover the evolutionary constraints and harmful mutations of potatoes, and the first two-dimensional map of harmful mutations of potatoes was drawn.

  Using the map information, the researchers put forward a counterintuitive inbred line cultivation method and developed a new model for whole genome prediction, which made the potato yield prediction reach unprecedented accuracy. In addition, the model can accurately estimate the breeding value according to genotype and harmful mutation information, better help breeding experts to make early breeding decisions, further reduce breeding costs, shorten potato breeding cycle and quickly cultivate high-yield and high-quality potato varieties.

  This research made China stand in the leading position in the world in the basic theory and technology of potato breeding, and was funded by the Ministry of Science and Technology, the National Natural Science Foundation of China and China Academy of Agricultural Sciences.

  So, what are the implications of this research for other crop breeding? In this regard, Li Jiayang, an academician of China Academy of Sciences (director of Yazhouwan Laboratory and researcher of Institute of Genetics and Developmental Biology, Chinese Academy of Sciences) said, "The research result of Huang Sanwen’s team will not only be for potatoes, but also for grain, oil, fruits, vegetables and tea."

  Zhong Kang, an academician of China Academy of Sciences (researcher of Institute of Botany, Chinese Academy of Sciences) commented: "This research by Huang Sanwen’s team is a milestone achievement in potato breeding, which indicates that crop breeding has entered a new era, that is, breeders can’t just pay attention to their own ‘ Three points per acre ’ It is even more necessary to think about the new strategy of breeding from a larger evolutionary dimension. "

  "The research finally found the genetic basis of counterintuitive screening, developed a new genome-wide prediction model and applied it to the early decision-making of hybrid potato breeding, marking that China’s potato breeding has definitely reached the international frontier." Professor Lai Jinsheng of China Agricultural University (Director of National Maize Improvement Center) said.

Running to lose weight, these new skills make you more relaxed.

Every year, many people choose running as a weapon to lose weight. However, the situation that they can’t cope with the results is everywhere, the effect is not obvious, and then they are discouraged and give up. This failure history is constantly staged.

Andrew Ka Stoll, a running coach in Lake Mamos, California, USA, gave you a new solution. He put forward the exercise plan is:Shorter time, higher intensity, five times a week, each time within 20 minutes.

This program can not only help you lose those excess weights, but also effectively reduce the risk of cholesterol and cardiovascular and cerebrovascular diseases, and help maintain the elasticity of your skin.

Step out of the right running rhythm

Many people misunderstand running and regard it as a pure strength challenge, madly improving speed and running distance, but in fact,Stability and rhythm are the essence of running..

At first, we should give priority to comfort and relaxation, and every step should be strong and stable. Once you are short of breath and your heart beats rapidly, it means that you have crossed your comfort zone.

Although this kind of high-intensity running may consume more calories in a short time, it will have a negative impact on the endurance of the body in the long run, causing you to feel tired and even lose your interest and motivation in running.

The gradual rhythm can paint an ideal running picture, and the wind in your ear and the rhythm of breathing find harmony in this stable rhythm.

Beginners should be patient and not driven by short-term benefits. The correct running rhythm will take you to the other side of health.

Speed and terrain: dual elements of running

Running can’t be static. If you always run at the same speed and terrain, the human body will soon adapt to it, and the weight loss effect will gradually decrease.

Therefore, it is very important to pay attention to the change of speed and terrain to maintain running efficiency.

Through different speed training, it can help the energy in the body run smoothly like a small mountain stream.More conducive to burning fat.

Changing the choice of running terrain, such as changing from flat to climbing, can undoubtedly increase the load on the body and consume more calories.

Changing the speed and terrain can not only challenge yourself and improve running endurance, but more importantly, it can stimulate muscles, accelerate metabolism and improve the long-term weight loss effect of running.

At the same time, such changes can also improve the fun of running, break the routine and make the exercise process no longer dull.

Diet regulation: the other side of losing weight

In the process of losing weight, many people tend to have a misunderstanding, that is, they are full of determination and anxiety to lose weight, but they ignore the adjustment of diet intake.

On the contrary, in fact, scientific diet control is one of the key rules for success in the process of losing weight.

For example, after heavy running training, people often feel extremely hungry.

However, if you choose to eat too much, regardless of controlling your appetite, it is likely that all the calories you run will be replenished in the end, and your efforts to lose weight will become stillborn.

Then, in the process of running to lose weight, how should we scientifically adjust the diet?

The first thing to make sure isOn the premise of ensuring basic nutrition, formulate and adjust the diet structure in a timely manner..

For example, after tired running, our body needs rich nutrition to recover. At this time, we can choose to eat carbohydrates contained in vegetables, fruits and staple foods. These are good at helping to restore physical strength, and at the same time, we will not introduce too many extra calories.

Of course, the change of eating habits does not mean that we should deliberately suppress our appetite. After all, physical and mental pleasure is also an important factor in maintaining exercise motivation.

Secondly, we should learnGrasp the intake time of dietAvoid eating too much before running or eating immediately after running, which is likely to burden the gastrointestinal tract and affect the running effect.

Generally speaking, a good energy supply and recovery can be ensured by eating one to two hours before running, and supplementing enough protein and carbohydrates, as well as proper amount of fat, within the next day.

Therefore, when we run to lose weight, we should not only pay attention to speed and time, but also consider many factors such as terrain and food intake, so as to achieve the ideal weight loss effect.

As long as we carry out this plan persistently, I believe it is only a matter of time before we reach the goal of losing weight.